AFM images were also obtained using a scanning probe

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steroids drugs It was found that low DP oligomers of the second generation polycarbonate dendronised monomer had an approximately spherical shape, which tended towards cylindrical as the DP increased. The polymer at a DP of 16 had dimensions of approximately 10 nm diameter by 4 nm thickness. AFM images were also obtained using a scanning probe microscope MultiMode Nanoscope IV. steroids drugs

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steroid “We are very pleased with the rapid progress we have made in the development of a portfolio of promising therapeutics and grateful for the continued support of our investors,” said Benjamin Yerxa steroids steroids, President. “This financing will be used to continue the clinical evaluation of our lead product, ENV515 for glaucoma, through phase 2 studies and to advance two other products in our pipeline through key data milestones.”Envisia is focused on the development of novel ocular therapeutics, with current programs in glaucoma steroids steroids, diabetic macular edema (DME) and age related macular degeneration (AMD).ENV515 for glaucoma, Envisia’s lead product candidate, is a fully biodegradable PRINT particle formulation of a marketed prostaglandin analog travoprost that has the potential to lower intraocular pressure (IOP) for more than six months from a single dose and may be effective in addressing the issue of poor patient compliance that exists today with daily eye drops.Enrollment has been completed in the second cohort (low dose formulation) of the phase 2a study and safety and efficacy data at the three month time point is expected to be available in May 2016.A third cohort (high dose formulation) is expected to enter clinical testing in mid year 2016.ENV1105 for DME is an intravitreal, fully biodegradable PRINT particle formulation of the steroid dexamethasone with a six month minimum duration of action.The pre Investigational New Drug (IND) meeting was successfully conducted with the FDA in the first quarter of 2016.The Company expects to advance ENV1105 through preclinical testing and into clinical development in the first half of 2017.ENV1305 for AMD is a sustained release anti VEGF monoclonal antibody.Initiation of long term preclinical studies is planned for mid year 2016 to assess safety and pharmacokinetics.ABOUT ENVISIA THERAPEUTICSEnvisia Therapeutics is a privately held biotechnology company focused on the development of novel ocular therapies. Envisia is leveraging the unique and powerful properties of the PRINT technology platform to develop therapies for a variety of ocular conditions, beginning with ENV515 for glaucoma steroid.

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